NBK Polyclonal Antibody, 50ul Liquid Handling ＆Storage The protein encoded by DGKZ

The protein encoded by DGKZ (diacylglycerol kinase zeta) belongs to the eukaryotic diacylglycerol kinase family

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Also in fetal lung fibroblasts and fetal brain

a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable

Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain

NBK Polyclonal Antibody, 50ul Liquid Handling ＆Storage The protein encoded by DGKZBcl 2 interacting killer encoded by BIK shares a critical BH3 domain with other death promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro apoptotic activity, and for interaction with anti apoptotic members of the BCL2 family, and viral survival promoting proteins. Since the activity of this protein is suppressed in the presence of survival promoting proteins, it is suggested as a likely target for anti apoptotic proteins.