GGT6 Rabbit Polyclonal Antibody, 50ul Purification Although 2 transmembrane domains are

Although 2 transmembrane domains are predicted

The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration

Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE)

for proteasomal degradation

Gene Ontology (GO) annotations related to RNF144B include ligase activity and ubiquitin-protein transferase activity

GGT6 Rabbit Polyclonal Antibody, 50ul Purification Although 2 transmembrane domains areGGT6 belongs to the gamma glutamyltransferase (GGT; EC 2. 3. 2. 2) gene family. GGT is a membrane bound extracellular enzyme that cleaves gamma glutamyl peptide bonds in glutathione and other peptides and transfers the gamma glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al. 2008