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Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter The protein encoded by PKN1

SKU: 38720436458

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Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter The protein encoded by PKN1Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1 or separase which

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Description

The protein encoded by PKN1 (protein kinase N1) belongs to the protein kinase C superfamily

The syndecan 1 encoded by SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family

an interaction that explains the importance of this collagen in organizing matrix components

The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct

Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression

Separase(Phospho Ser801) Polyclonal Antibody, 100ul Centrifugal Filter The protein encoded by PKN1Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1 or separase which

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