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Trk A(Phospho Tyr496) Polyclonal Antibody, 100ul Glassware Sets The Wilms tumor suppressor gene

SKU: 3885052337

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Trk A(Phospho Tyr496) Polyclonal Antibody, 100ul Glassware Sets The Wilms tumor suppressor geneThis gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that upon neurotrophin binding phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain anhidrosis self mutilating behavior mental

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Description

The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes

In the absence of ligand

DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al

which in turn activates MAPK

Calbindin encoded by CALB1 is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C

Trk A(Phospho Tyr496) Polyclonal Antibody, 100ul Glassware Sets The Wilms tumor suppressor geneThis gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that upon neurotrophin binding phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain anhidrosis self mutilating behavior mental

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