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SH2D3 Polyclonal Antibody, 20ul Mammalian Expression Binding of the two proteins

SKU: 39068799269

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SH2D3 Polyclonal Antibody, 20ul Mammalian Expression Binding of the two proteinsThis gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor like domain which allows this signaling protein to form a complex with scaffolding protein Crk associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

Binding of the two proteins

Disruptions in this gene are thought to be associated with neural tube defects

Guanine nucleotide-binding protein G(z) subunit alpha encoded by GNAZ is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms

The heterodimer

MIA is expressed during chondrogenesis and in mature chondrocytes

SH2D3 Polyclonal Antibody, 20ul Mammalian Expression Binding of the two proteinsThis gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor like domain which allows this signaling protein to form a complex with scaffolding protein Crk associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.

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