MYBPC3 Polyclonal Antibody, 20ul Site-directed Mutagenesis variations in a region containing

variations in a region containing this gene have been associated with inner ear malformations

It is a member of the MADS (MCM1| Agamous| Deficiens| and SRF) box superfamily of transcription factors

The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane

Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity

and then form homodimers

MYBPC3 Polyclonal Antibody, 20ul Site-directed Mutagenesis variations in a region containingMYBPC3 encodes the cardiac isoform of myosin binding protein C. Myosin binding protein C is a myosin associated protein found in the cross bridge bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction.