DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture a rare autosomal recessive form

a rare autosomal recessive form of night blindness

Multiple alternatively spliced variants have been described for this gene

This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye

This gene encodes a member of the SWI2/SNF2 family of proteins

The external domain mediates cell attachment to the extracellular matrix molecule vitronectin

DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture a rare autosomal recessive formThe protein encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and