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GCH1 Polyclonal Antibody, 20ul Enzyme Activity Assays It may play a role

SKU: 39271214250

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SEK97.20 SEK147.20

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GCH1 Polyclonal Antibody, 20ul Enzyme Activity Assays It may play a roleThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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Description

It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport

perfect for researchers and scientists looking to push boundaries and discover new breakthroughs

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF| and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II)| making it available for initiation of gene expression

whereas the other four melanocortin receptors recognize a variety of melanocortin ligands

TEAD1 (TEA domain transcription factor 1) encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family

GCH1 Polyclonal Antibody, 20ul Enzyme Activity Assays It may play a roleThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8 dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa responsive dystonia.

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