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NBPF6 Polyclonal Antibody, 20ul Buffers & Solutions p11) with ARHH/TTF

SKU: 39373239842

4.0
USD111.00 USD143.00

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NBPF6 Polyclonal Antibody, 20ul Buffers & Solutions p11) with ARHH/TTFThis gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number

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Description

p11) with ARHH/TTF

The encoded protein functions as a receptor for ubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy

Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s| with the greatest degree of conservation in the G domains of the proteins

The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains

Mutation in this gene has been associated with Naxos disease

NBPF6 Polyclonal Antibody, 20ul Buffers & Solutions p11) with ARHH/TTFThis gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number

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