PA26 Polyclonal Antibody, 100ul Serological Pipets It acts both as a

It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs)

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Alternative splicing results in multiple transcript variants that encode different isoforms

which function in various biological processes including axon guidance

Multiple pseudogenes of this gene are located on chromosome 1

PA26 Polyclonal Antibody, 100ul Serological Pipets It acts both as aSESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized