Siah-2 Polyclonal Antibody, 50ul Measuring Instruments also known as TOME1 (Trigger

also known as TOME1 (Trigger of mitotic entry protein 1) and GRCC8 (Gene-rich cluster protein C8)

but in contrast to other family members

ensuring the highest level of accuracy and purity

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family

The encoded protein binds only GTP but has no GTPase activity

Siah-2 Polyclonal Antibody, 50ul Measuring Instruments also known as TOME1 (TriggerSIAH2 encodes E3 ubiquitin protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.