MDMX Polyclonal Antibody, 20ul Sample Library Tubes The hypothalamic suprachiasmatic nucleus appears

The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin

The human gene is both the structural and functional homolog of the yeast scERV1 gene

The protein encoded by ATR (ATR serine/threonine kinase) belongs the PI3/PI4-kinase family

This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites

making it ideal for various experimental studies

MDMX Polyclonal Antibody, 20ul Sample Library Tubes The hypothalamic suprachiasmatic nucleus appearsMDM4 encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.