ANXA8 Rabbit Polyclonal Antibody, 50ul Organelle Studies Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene

Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2)

Pseudogenes of this gene are located on chromosomes 9

This gene encodes a member of the membrane-spanning 4A gene family

a class of proteins involved in the phosphorylation of sugars as they enter a cell

ANXA8 Rabbit Polyclonal Antibody, 50ul Organelle Studies Alternatively spliced transcript variants encodingThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.