Cbl Polyclonal Antibody, 50ul[BT-AP01263] Cell fragmentation and collection Aberrant expression of this gene

Aberrant expression of this gene in adult tissues is associated with tumorigenesis

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2

tissue specificity:Expressed in lung and macrophages

delaying the onset of anaphase and ensuring proper chromosome segregation

multiple polyadenylation sites are found in the 3' UTR

Cbl Polyclonal Antibody, 50ul[BT-AP01263] Cell fragmentation and collection Aberrant expression of this geneCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated