ZNRF2 Polyclonal Antibody, 50ul Antibodies The protein encoded by this

The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system

Has over 50-fold higher inhibitory activity when phosphorylated

The human genome contains many pseudogenes similar to this locus

delaying the onset of anaphase and ensuring proper chromosome segregation

a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network

ZNRF2 Polyclonal Antibody, 50ul Antibodies The protein encoded by thisMay play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.