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hCAP-G Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) This gene is a direct

SKU: 40389902230

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hCAP-G Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) This gene is a directNCAPG (non SMC condensin I complex subunit G) encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for NCAPG on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants.

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Description

This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators

and other cellular interactions important for immune response and surveillance

there is no correlation between the repeat number and the disease

CBL has been found to be mutated or translocated in many cancers including acute myeloid leukaemia

Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene

hCAP-G Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) This gene is a directNCAPG (non SMC condensin I complex subunit G) encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There are pseudogenes for NCAPG on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants.

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