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IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation Among its related pathways are

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IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation Among its related pathways areIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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Description

Among its related pathways are protein ubiquitylation

A processed non-transcribed pseudogene located in an intron of a sodium transporter gene on chromosome 5 has been defined for this gene

which is expressed exclusively in hematopoietic cells

Knockout studies in mice suggest that the different receptors

Members of the F-box protein family| such as FBXL12| are characterized by an approximately 40-amino acid F-box motif

IGF-IR Polyclonal Antibody, 100ul[BT-AP04398] Polyclonal Antibody Preparation Among its related pathways areIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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