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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies and in the renal tubular

SKU: 41156754948

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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies and in the renal tubularThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

and in the renal tubular response to proteinuria

Directly mediates protection against viral and bacterial genital infections (By similarity)

as well as in peripheral sites such as the small intestine and heart

Mutations in GDI1 have been linked to X-linked nonspecific mental retardation

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Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies and in the renal tubularThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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