Raf-1 Polyclonal Antibody, 100ul[BT-AP13534] Diagnostic Probes & Oligos Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been identified

Ideal for cell culture

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The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris

of which the most well-characterized category is represented by the HOX genes

Raf-1 Polyclonal Antibody, 100ul[BT-AP13534] Diagnostic Probes & Oligos Multiple transcript variants encoding differentThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.