Rat Glutamate[NMDA] Receptor Subunit Epsilon-2, GRIN2B ELISA Kit, 96T Antibodies As a scaffold protein involved

As a scaffold protein involved in cell polarization processes| this protein binds to many other proteins

The encoded protein is a strong inducer of lymphocyte apoptosis

Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852

At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene

mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3)

Rat Glutamate[NMDA] Receptor Subunit Epsilon-2, GRIN2B ELISA Kit, 96T Antibodies As a scaffold protein involvedComponent of NMDA receptor complexes that function as heterotetrameric, ligand gated ion Channels with high calcium permeability and voltage dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate Channel inhibition by Mg(2+) (PubMed: 1350383, PubMed: 19910922, PubMed: 21677647, PubMed: 24876489,