DTBP1 Rabbit Polyclonal Antibody, 20ul Peptide Modification (PMID: 20173098 ) From BLAST

(PMID: 20173098 ) From BLAST result

Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

It may be involved in breast cancer

but preventing subsequent viral fusion and release of viral contents into the cytosol

and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system

DTBP1 Rabbit Polyclonal Antibody, 20ul Peptide Modification (PMID: 20173098 ) From BLASTThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes platelet dense granules and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome related organelles complex 1 (BLOC 1) and binds to alpha and beta dystrobrevins which are components of the dystrophin associated protein complex (DPC). Mutations in this gene are associated with Hermansky Pudlak syndrome