Lamin B1 Polyclonal Antibody, 50ul[BT-AP04935] Biomatrix Mutations in this gene have

Mutations in this gene have been associated with WHIM (warts

suggesting that this gene may be involved in tumor progression

Mutations in this gene have been associated with adducted thumb-clubfoot syndrome

and inhibit the activity of JAK2 kinase

This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation| and an inducible nuclear component

Lamin B1 Polyclonal Antibody, 50ul[BT-AP04935] Biomatrix Mutations in this gene haveLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.