IBP5 Polyclonal Antibody, 100ul Molecular Sciences Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding distinct isoforms have been found

Enhances the transcriptional repressor activity of NR1D1 through stabilization of NR1D1 protein levels by preventing its ubiquitination and subsequent degradation (PubMed: 18235501

TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs

A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin

IF staining of Hsp70 in heat shocked HeLa cells results in cytoplasmic staining

IBP5 Polyclonal Antibody, 100ul Molecular Sciences Multiple alternatively spliced transcript variantsIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,Contains 1 IGFBP N terminal domain.,Contains 1 thyroglobulin type 1 domain.,tissue specificity: Osteosarcoma, and at lower levels in liver, kidney and brain.,