Histone H4 (Di Methyl Lys59) Polyclonal Antibody, 20ul Drug Development and Evaluation Mutations in this gene are

Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens

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Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound

FAM48A is required for MAP kinase p38 activation during gastrulation and for starvation-induced ATG9A trafficking during autophagy

An important paralog of this gene is CD300LG

Histone H4 (Di Methyl Lys59) Polyclonal Antibody, 20ul Drug Development and Evaluation Mutations in this gene areHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.