LST8 Polyclonal Antibody, 50ul Miscellaneous NEIL2 belongs to a class

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family

3-dehydroacyl-CoA + NADPH

Affected individuals display mottled pigmentation

The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100

a similar D4Z4 repeat array has been identified on chromosome 10

LST8 Polyclonal Antibody, 50ul Miscellaneous NEIL2 belongs to a classUnessential component of the TORC1 complex and essential component of the TORC2 complex. TORC1 controls cell growth in response to environmental signals, and is inactivated by nutrient limitation and environmental stress. Within TORC1, LST8 interacts directly with FRAP1 and enhances its kinase activity. In nutrient poor conditions, stabilizes the FRAP1 RAPTOR interaction and favors RAPTOR mediated inhibition of FRAP1 activity. TORC2 controls polarity