UBE2W Polyclonal Antibody, 20ul Stepper Mutations in this gene result

Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome

This gene is almost exclusively expressed in the brain

This receptor transduces the growth promoting signal of IL21

Binds TCF4 and RB1

or with the TCF3 (E2A) gene on chromosome 19

UBE2W Polyclonal Antibody, 20ul Stepper Mutations in this gene resultThis gene encodes a nuclear localized ubiquitin conjugating enzyme (E2) that, along with ubiquitin activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple