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Vav(Phospho Tyr174) Polyclonal Antibody, 100ul NGS Oligos Mediates the mitogen- and stress-induced

SKU: 42755737439

4.8
PLN141.00 PLN187.00

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Vav(Phospho Tyr174) Polyclonal Antibody, 100ul NGS Oligos Mediates the mitogen- and stress-inducedThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.

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Description

Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14)

1-10μl volumes

Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions

and AQP5 reside in a cluster on chromosome 12q13

thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804)

Vav(Phospho Tyr174) Polyclonal Antibody, 100ul NGS Oligos Mediates the mitogen- and stress-inducedThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.

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