SH2B3 Polyclonal Antibody, 100ul Lentiviral Packaging This gene encodes a protein

This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development

Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080)| LYL1 (MIM 151440)| E2A (MIM 147141)| and SCL (MIM 187040)

Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy

This gene is broadly expressed

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SH2B3 Polyclonal Antibody, 100ul Lentiviral Packaging This gene encodes a proteinThis gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced