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MAO-A Polyclonal Antibody, 50ul[BT-AP05201] Cell Transfection B cell adapter molecule (BAM32)

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MAO-A Polyclonal Antibody, 50ul[BT-AP05201] Cell Transfection B cell adapter molecule (BAM32)MAOA is one of two neighboring gene family members that encode Amine oxidase [flavin containing] A which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

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Description

B cell adapter molecule (BAM32) is also designated dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein

Reciprocal translocations between chromosomes 17 and 22| where this gene and the gene for platelet-derived growth factor beta are located| are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans| resulting from unregulated expression of the growth factor

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton

including adrenal gland

Overexpression of this gene has been associated with acute myelocytic leukemia

MAO-A Polyclonal Antibody, 50ul[BT-AP05201] Cell Transfection B cell adapter molecule (BAM32)MAOA is one of two neighboring gene family members that encode Amine oxidase [flavin containing] A which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

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