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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07022] Nucleic Acid Amplification and one of the most

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07022] Nucleic Acid Amplification and one of the mostPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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Description

and one of the most basic

This gene is expressed primarily in the placenta and ovarian granulosa cells

somatic and familial gastrointestinal stromal tumors

Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif)

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2)

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07022] Nucleic Acid Amplification and one of the mostPDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. PDGFRB is flanked on chromosome 5 by the genes for

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