RT31 Polyclonal Antibody, 100ul Cell Proliferation Mutations in this gene cause

Mutations in this gene cause VLDLR-associated cerebellar hypoplasia

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane

Expressed at lower level in placenta

This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation

and are therefore similar to the constitutively active forms of oncogenic forms of Ras

RT31 Polyclonal Antibody, 100ul Cell Proliferation Mutations in this gene causeMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S