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IL-13R Alpha2 Polyclonal Antibody, 50ul[BT-AP04441] Liquid Storage Consumables Expression of this gene may

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IL-13R Alpha2 Polyclonal Antibody, 50ul[BT-AP04441] Liquid Storage Consumables Expression of this gene mayThe interleukin 13 receptor subunit alpha 2 encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

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Description

Expression of this gene may be downregulated in colon and rectal cancer

followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain

The encoded protein is an integral membrane protein and may be localized to the basolateral membrane

it may functionally substitute for c-Jun during development in mice

Elevated expression of this gene has been observed in oral squamous cell carcinoma

IL-13R Alpha2 Polyclonal Antibody, 50ul[BT-AP04441] Liquid Storage Consumables Expression of this gene mayThe interleukin 13 receptor subunit alpha 2 encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

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