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TRIM2 Rabbit Polyclonal Antibody, 100ul Diagnostic Probes & Oligos PGR encodes a member of

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TRIM2 Rabbit Polyclonal Antibody, 100ul Diagnostic Probes & Oligos PGR encodes a member ofThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3 ubiquitin ligase in proteasome mediated degradation of target proteins. Mutations in this gene can cause early onset axonal neuropathy. Alternative

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Description

PGR encodes a member of the steroid receptor superfamily

Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus

and which specifically associates with spliced mRNA and not with unspliced pre-mRNA

High mobility group box 1 plays a role in several cellular processes

Alternatively spliced transcript variants have been described for DUS2

TRIM2 Rabbit Polyclonal Antibody, 100ul Diagnostic Probes & Oligos PGR encodes a member ofThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains a RING a B box type 1 and a B box type 2 and a coiled coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3 ubiquitin ligase in proteasome mediated degradation of target proteins. Mutations in this gene can cause early onset axonal neuropathy. Alternative

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