NTCP2 Rabbit Polyclonal Antibody, 20ul Serological Pipets brain and liver

brain and liver

Defects in this gene are frequently found in patients with prostate tumors

Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions

This gene encodes a member of the F-box protein family which is characterized by the F-box motif

This is the rate-limiting step in the de novo synthesis of guanine nucleotides

NTCP2 Rabbit Polyclonal Antibody, 20ul Serological Pipets brain and liverThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines