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Flk-1 Polyclonal Antibody, 20ul[BT-AP03269] Centrifugal Filter Defects in APC cause familial

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Flk-1 Polyclonal Antibody, 20ul[BT-AP03269] Centrifugal Filter Defects in APC cause familialVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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Description

Defects in APC cause familial adenomatous polyposis (FAP)

The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif

Studies of the mouse and chick homologs revealed roles in midbrain and limb development

aspartate and glutamate metabolism

Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics

Flk-1 Polyclonal Antibody, 20ul[BT-AP03269] Centrifugal Filter Defects in APC cause familialVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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