SPAK(Phospho Ser309) Polyclonal Antibody, 20ul Aspirating Pipets The LIM/double zinc-finger motif found

The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation

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Found in a mRNA splicing-dependent exon junction complex (EJC) with DEK

interact with membrane-bound receptors

SPAK(Phospho Ser309) Polyclonal Antibody, 20ul Aspirating Pipets The LIM/double zinc-finger motif foundThis gene encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the