Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Alternative splicing has been observed

Alternative splicing has been observed in this gene

SEPT3 belongs to the septin family of GTPases

The protein encoded by this gene is a member of the cyclin family of proteins

This gene encodes a glycosylated phosphoprotein with a leucine zipper motif| two helix-loop-helix motifs (I repeats) that are similar to domains found in the TFII-I family of transcription factors| one CHARLIE8 transposable element-like sequence| and a BED zinc finger

Alternative splicing may result in several transcript variants| however

Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Alternative splicing has been observedDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).