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Integrin Alpha3 Polyclonal Antibody, 50ul[BT-AP04572] Pipette Controller The product of PEX5 (peroxisomal

SKU: 45954269086

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Integrin Alpha3 Polyclonal Antibody, 50ul[BT-AP04572] Pipette Controller The product of PEX5 (peroxisomalITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia.

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Description

The product of PEX5 (peroxisomal biogenesis factor 5) binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import

and active when dephosphorylated at this site

Contactin-4 is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system

but a deletion of DDX3Y is not complemented by DDX3X

and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease

Integrin Alpha3 Polyclonal Antibody, 50ul[BT-AP04572] Pipette Controller The product of PEX5 (peroxisomalITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia.

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