Dok-2(Phospho Tyr299) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification The type I cytokeratins are

The type I cytokeratins are clustered in a region of chromosome 17q12-q21

SVOP (SV2 Related Protein) is a Protein Coding gene

and BHRF-1

a group of coiled-coil proteins localized to the Golgi

The encoded protein interacts with the C-terminal domain of ezrin| an ERM protein| and may play a role in cell adhesion and migration

Dok-2(Phospho Tyr299) Polyclonal Antibody, 20ul DNA/RNA Isolation & Purification The type I cytokeratins areThe protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.