ANTR1 Polyclonal Antibody, 100ul Culture Tubes SNCA may serve to integrate

SNCA may serve to integrate presynaptic signaling and membrane trafficking

A pseudogene of this gene is found on chromosome 22

Alternative splicing of this gene results in two transcript variants

Mutations in PDHA1 are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome

|Contains 9 SRCR domains

ANTR1 Polyclonal Antibody, 100ul Culture Tubes SNCA may serve to integrateThis gene encodes a type I transmembrane protein and is a tumor specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol