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Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing |subunit:Heterotetramer that consists of two

SKU: 46439814374

4.1
SEK141.00 SEK189.00

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Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing |subunit:Heterotetramer that consists of twoThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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Description

|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit

and may play a role in regulating the apoptotic events in the dying cell

Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19

tissue specificity:Isoform 1 is highly expressed in adult and fetal heart

TORC1 binds to and is inhibited by FKBP12-rapamycin

Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing |subunit:Heterotetramer that consists of twoThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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