Apaf-1-ALT Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Aberrant splice variants expressed in

Aberrant splice variants expressed in tumor cell lines have also been described

Actin alpha cardiac muscle 1/Actin alpha skeletal muscle/Actin aortic smooth muscle/Actin gamma-enteric smooth muscle encoded by ACTC1 belongs to the actin family which is comprised of three main groups of actin isoforms

PP-4 (PP-X) subfamily

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Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics

Apaf-1-ALT Polyclonal Antibody, 50ul Peripheral Blood Separation Tube Aberrant splice variants expressed inAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent