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GIT1 Polyclonal Antibody, 20ul Cell Transfection Alternatively spliced transcript variants encoding

SKU: 47093020863

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GIT1 Polyclonal Antibody, 20ul Cell Transfection Alternatively spliced transcript variants encodingARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine

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Description

Alternatively spliced transcript variants encoding multiple isoforms have been observed for CUL3

In contrast to HMWK

ediates cell-cell adhesion in a calcium-dependent manner (By similarity)

The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion

thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery

GIT1 Polyclonal Antibody, 20ul Cell Transfection Alternatively spliced transcript variants encodingARF GTPase activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene. GIT1 contains an ARFGAP domain, Anykrin repeats and a GRK interacting domain. The Arf GAP domain, which enables it to act as a GTPase activating protein (GAP) for the Arf family of GTPases, has been shown to be involved in phosphorylation and inhibition of the ADRB2. If synaptic localization of GIT1 is disturbed, then this is known to affect dendritic spine

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