H2AZ Polyclonal Antibody, 50ul Thermal Control |PTM:Sumoylation on Lys-428 is promoted

|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4

which function in protein-protein interactions

and undergoes alternative splicing to produce two isoforms

Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype

phagocytosis

H2AZ Polyclonal Antibody, 50ul Thermal Control |PTM:Sumoylation on Lys-428 is promotedHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.