SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody, 50ul Dry Bath Individuals homozygous for a mutation

Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion

ccessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids

This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation

The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme

The protein plays a role in immunity| by restricting transmission of foreign DNA such as viruses

SF3B1(Phospho-Thr313) Rabbit Polyclonal Antibody, 50ul Dry Bath Individuals homozygous for a mutationThis gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b together with splicing factor 3a and a 12S RNA unit forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b 3a complex binds pre mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre mRNA. Splicing factor 3b is also a component of the minor U12 type spliceosome. The