NMRL1 Rabbit Polyclonal Antibody, 50ul Enzyme Activity Assays Mutations in this gene are

Mutations in this gene are the most common cause of Fanconi anemia

The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine

MARK1 is a Protein Coding gene

Contains 5 WD repeats

Additional isoforms produced by alternative splicing seem to exist

NMRL1 Rabbit Polyclonal Antibody, 50ul Enzyme Activity Assays Mutations in this gene areThis gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF kappaB in a ubiquitylation dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3 mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants.