TTR mouse Monoclonal Antibody(3B5), 20ul Drug Development and Evaluation This locus encodes a member

This locus encodes a member of the glycerate kinase type-2 family

acting in cis to limit the elongation of individual chromosome ends

CLIC6 is part of a large triplicated region found on chromosomes 1

Glutathione S-transferase theta-1 encoded by GSTT1 is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds

The encoded protein has multiple proposed functions

TTR mouse Monoclonal Antibody(3B5), 20ul Drug Development and Evaluation This locus encodes a memberThis gene encodes transthyretin, one of the three prealbumins including alpha 1 antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported most mutations are related to amyloid