GCKR Polyclonal Antibody, 50ul Human Genome Knockout Libraries Required for nuclear receptor-mediated transactivation

Required for nuclear receptor-mediated transactivation

and cytoplasmic signaling proteins

Required for normal assembly of mitotic spindles

It associates with Ret to transduce Ret-mediated processes such as axonal projection

which has increased affinity for huntingtin protein with expanded polyglutamine repeats

GCKR Polyclonal Antibody, 50ul Human Genome Knockout Libraries Required for nuclear receptor-mediated transactivationGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).