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UN13B Rabbit Polyclonal Antibody, 100ul Bottles Mutations in this gene are

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UN13B Rabbit Polyclonal Antibody, 100ul Bottles Mutations in this gene areThis gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog and contains 3 C2 domains and a diacylglycerol binding C1 domain. Hyperglycemia increases the levels of diacylglycerol which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other

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Description

Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females

Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6

and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway

an inducible heme oxygenase-1 and a constitutive heme oxygenase-2

TTF1 shares the symbol/alias TFF1 with another gene

UN13B Rabbit Polyclonal Antibody, 100ul Bottles Mutations in this gene areThis gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog and contains 3 C2 domains and a diacylglycerol binding C1 domain. Hyperglycemia increases the levels of diacylglycerol which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other

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