TAB3 Polyclonal Antibody, 100ul Vessels Peroxisome proliferator activated receptor gamma
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TAB3 Polyclonal Antibody, 100ul Vessels Peroxisome proliferator activated receptor gammaThe product of this gene functions in the NF kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2 TAB2, forms a ternary complex with the protein kinase MAP3K7 TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro inflammatory cytokines TNF or IL 1. Subsequent MAP3K7 TAK1 kinase activity triggers a signaling cascade leading to activation of the NF kappaB transcription
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